A sweeping germ’s-eye view of history from human origins to global pandemics

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our
evolutionary past, and why its growth is acceleratedby technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues in patterns of wealth, health,
power, and inequality. He also tells the story of humanity’s escape from infectious disease–a triumph that makes life as we know it possible, yet destabilizes the environment and fosters new diseases.

Panoramic in scope, Plagues upon the Earth traces the role of disease in the transition to farming, the spread of cities, the advance of transportation, and the stupendous increase in human population. Harper offers a new interpretation of humanity’s path to control over
infectious disease–one where rising evolutionary threats constantly push back against human progress, and where the devastating effects of modernization contribute to the great divergence between societies. The book reminds us that human health is globally
interdependent–and inseparable from the well-being of the planet itself.

Putting the COVID-19 pandemic in perspective, Plagues upon the Earth tells the story of how we got here as a species, and it may help us decide where we want to go.

A sweeping new history of how climate change and disease helped bring down the Roman Empire Here is the monumental retelling of one of the most consequential chapters of human history: the fall of the Roman Empire. The Fate of Rome is the first book to examine the catastrophic role that climate change and infectious diseases played in the collapse of Rome’s power–a story of nature’s triumph over human ambition. Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes readers from Rome’s pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted. Harper describes how the Romans were resilient in the face of enormous environmental stress, until the besieged empire could no longer withstand the combined challenges of a “little ice age” and recurrent outbreaks of bubonic plague. A poignant reflection on humanity’s intimate relationship with the environment, The Fate of Rome provides a sweeping account of how one of history’s greatest civilizations encountered, endured, yet ultimately succumbed to the cumulative burden of nature’s violence. The example of Rome is a timely reminder that climate change and germ evolution have shaped the world we inhabit–in ways that are surprising and profound. Author bio: Kyle Harper is professor of classics and letters and senior vice president and provost at the University of Oklahoma. He is the author of Slavery in the Late Roman World, AD 275-425 and From Shame to Sin: The Christian Transformation of Sexual Morality in Late Antiquity. He lives in Norman, Oklahoma.