A vivid, sweeping, and “fact-filled” (Booklist, starred review) history of mankind’s battles with infectious disease that “contextualizes the COVID-19 pandemic” (Publishers Weekly)–for readers of the #1 New York Times bestsellers Yuval Harari’s Sapiens and John Barry’s The Great Influenza.

For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion–quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles–resulting in an urbanized, globalized, and unimaginably wealthy world.

However, our development has lately become precarious. Climate and population fluctuations and factors such as global trade have left us more vulnerable than ever to newly emerging plagues. Greater global cooperation toward sustainable health is urgently required–such as the international efforts to manufacture and distribute a COVID-19 vaccine–with millions of lives and trillions of dollars at stake.

“A timely, lucid look at the role of pandemics in history” (Kirkus Reviews), The Plague Cycle reveals the relationship between civilization, globalization, prosperity, and infectious disease over the past five millennia. It harnesses history, economics, and public health, and charts humanity’s remarkable progress, providing a fascinating and astute look at the cyclical nature of infectious disease.

America is in decline, and the rise of the East suggests a bleak future for the world’s only superpower – so goes the conventional wisdom. But what if the traditional measures of national status are no longer as important as they once were? What if America’s well-being was assessed according to entirely different factors?
In The Upside of Down, Charles Kenny argues that America’s so-called decline is only relative to the newfound success of other countries. And there is tremendous upside to life in a wealthier world: Americans can benefit from better choices and cheaper prices offered by schools and hospitals in rising countries, and, without leaving home, avail themselves of the new inventions and products those countries will produce. The key to thriving in this world is to move past the jeremiads about America’s deteriorating status and figure out how best to take advantage of its new role in a multipolar world. A refreshing antidote to prophecies of American decline, The Upside of Down offers a fresh and highly optimistic look at America’s future in a wealthier world.